Personalized anticancer vaccines

Anticancer vaccination is a broad sett of methods aimed at stimulating the immune response against tumor cells with the formation of immunological memory.

As a rule, antitumor vaccination is used to eliminate residual tumor (minimal residual disease) during remission after completion of the main course of treatment.

Since 2010, our scientists and clinicians have been developing a method for the use of DNA vaccines, as well as live bacterial anticancer vaccines.

The Center currently offers vaccine therapy for the following two diseases:

• B-cell non-Hodgkin lymphomas
  We prepare a personalized vaccine based on the patient’s own tumor cells.
  Tumor biopsy material is required befor the start of treatment, therefore it is best to seek this treatment during the period of diagnosis establishment.
  The process of vaccine preparation takes 4-6 months. During this time, the patient receives primary treatment including chemotherapy and surgical methods.
• Neuroblastoma
  Tumor material is required to confirm the presence of the antigen (marker) in a specific patient.
  Vaccination is indicated for patients with recurrent neuroblastoma or high-risk patients who have an inadequate response to primary therapy
  Vaccination involves the administration of these markers in the form of DNA into the patient’s body in order to train the immune system to recognize tumor cells and kill them.
  One course of vaccination includes three blocks of three vaccine injections and takes about three months.
  One month after the completion of vaccination, the immune response is assessed, and in case of its insufficiency, the course of vaccination may be repeated.